Supplementary data files to the initial Biorxiv submission of manuscript ‘A vaccine antigen central in influenza A(H5) virus antigenic space confers subtype-wide immunity’ by Kok et al. (2024).
Data S1 - A(H5) HA maximum likelihood phylogenetic tree.
Data S2 - Three-dimensional A(H5) influenza antigenic map.
Data S3 - Validation of the A(H5) antigenic map.
Data S4 - The effect of removing single individual antigens and sera on the map geometry.
Data S5 - A(H5) antigenic maps highlighting WHO candidate virus vaccines and antigens used in the ferret vaccination studies.
Data S6 - Merged antibody profiles upon vaccination with whole-inactivated vaccines containing engineered HA antigens.
Data S7 - Individual antibody profiles upon vaccination with whole-inactivated vaccines containing engineered HA antigens.
Data S8 - Merged antibody profiles of upon vaccination with split-inactivated vaccines containing wild-type HA antigens or the antigenically central HA antigen.
Data S9 - Individual antibody profiles of animals from the Giza vaccination-challenge study.
Data S10 - Individual antibody profiles of animals from the Sichuan vaccination-challenge study.
Note: interactive displays, especially Data S3, might take a while to load. Data S9 and S10 might not be properly displayed using the Chrome browser, hence Firefox is recommended.